About

Jeong-Sun SEO M.D., Ph.D.

Address : Genomic Medicine Institute Department of Biochemistry and Molecular Biology Seoul National University College of Medicine 28 Yongon-dong, Chongno-gu, Seoul 110-799, Korea
Telephone : (822) 740-8246
Fax : (822) 741-5423
mail : jeongsun@snu.ac.kr

Education

1976
Seoul National University College of Medicine (M.D.)
1980
Seoul National University, Biochemistry and Molecular Biology (Ph.D.)

Experience

1983 - present
Professor, Seoul National University, Korea
1981 - 1982
Visiting Scientist, Department of Molecular Genetics, NIH, USA
1983 - 1997
Chief, Division of Molecular Medicine, Cancer Research Center, SNU, Korea
1985 - present
Member of American Society for Microbiology, USA
1987 - present
Member of New York Academy of Science, USA
1990 - 1992
Visiting Professor, Rockefeller University, New York, USA
1995 - present
Executive director, Korea Genomic Medicine Foundation, Korea
1997 - present
Director, ILCHUN Genomic Medicine Institute, SNU MRC, Korea
1997 - present
Member of International Molecular Biology Network (IMBN)
2000 - 2007
Vice President, Korea Bio Venture Association, Korea
2003 - present
Member of The Korean Academy of Science and Technology, Korea
2004
Vice President, Korean Society of Medical Biochemistry and Molecular Biology
2004 - present
Chairman, Macrogen Inc., Korea
2005
President, Korea Genome Organization (KOGO), Korea
2005 - present
Member of American Society for Biochemistry and Molecular Biology (ASBMB)
2005 - present
Chairman, Biomedical hub advisory committee of IFEZ, Korea
2008 - present
President, Korea Bio Association, Korea
2008 - 2009
President, Korean Society for Biochemistry and Molecular Biology, Korea

Awards

2001
The Scientist Award of Year by The National Assembly of the Republic of Korea
2003
The 13th Excellence Paper Award by The Korean Federation of Science and Technology Societies
2007
Dongheon Award from KSBMB

Editorial Activity

1995 - present
Editor, Experimental & Molecular Medicine
2002 - present
Editor in Chief, Genomics & Informatics

Publications - 2010

Park H, Kim JI, Ju YS, Gokcumen O, Mills R, Kim S, Lee S, Suh D, Hong D, Kang H, Yoo YJ, Shin JY, Kim HJ, Yavartanoo M, Chang YW, Ha JS, Chong W, Hwang GR, Darvishi K, Kim H, Yang SJ, Yang KS, Kim H, Hurles M, Scherer S, Carter N, Thler-Smith C, Lee C & Seo JS.
Discovery of common Asian copy number variants using integrated high-resolution array CGH and massively parallel DNA sequencing. Nature Genetics, 2010 Feb.(in print)

Publications - 2009

Kim JI, Ju YS, Park H, Kim S, Lee S, Yi JH, Mudge J, Miller NA, Hong D, Bell CJ, Kim HS, Chung IS, Lee WC, Lee JS, Seo SH, Yun JY, Woo HN, Lee H, Suh D, Lee S, Kim HJ, Yavartnoo M, Kwak M, Zheng Y, Lee MK, Park H, Kim JY, Gokcumen O, Mills RE, Zaranek AW, Thakuria J, Wu X, Kim RW, Huntley JJ, Luo S, Schroth GP, Wu TD, Kim H, Yang KS, Park WY, Kim H, Church GM, Lee C, Kingsmore SF, Seo JS.
A highly annotated whole-genome sequence of a Korean individual. Nature. 2009 Aug 20;460(7258):1011-5. Epub 2009 Jul 8.

Publications - 2008

Gombojav B, Park H, Kim JI, Ju YS, Sung J, Cho SI, Lee MK, Ohrr H, Radnaabazar J, Seo JS.
Heritability and linkage study on heart rates in a Mongolian population. Exp Mol Med. 2008 Oct 31;40(5):558-64.
Tae-Hyung Kim, Tai-Qin Huang, Ja-June Jang, Man Ho Kim, Hyun-Jeong Kim, Jae-Seon Lee, Jeong Ki Pack, Jeong-Sun Seo and Woong-Yang Park.
Local exposure of 849 MHz and 1763 MHz radiofrequency radiation to mouse heads does not induce cell death or cell proliferation in brain. Exp Mol Med. 2008 June 30;40(3):294-303.
Perry GH, Ben-Dor A, Tsalenko A, Sampas N, Rodriguez-Revenga L, Tran CW, Scheffer A, Steinfeld I, Tsang P, Yamada NA, Park HS, Kim JI, Seo JS, Yakhini Z, Laderman S, Bruhn L, Lee C.
The Fine-scale and complex architecture of human copy-number variation. Am J Hum Genet. 2008 Mar;82(3):685-95.
Hansoo Park, Jong-Il Kim, Sung-Il Cho, Joohon Sung, Hyung-Lae Kim, Young Seok Ju, Gombojav Bayasgalan, Mi-Kyeong Lee and Jeong-Sun Seo.
Genome-wide Linkage Study for Plasma HDL Cholesterol Level in an Isolated Population of Mongolia. Genomics & Informatics. 2008 Mar;6(1):8-13.

Publications - 2006

Publications - 2005

Hwang JH, Ryu JK, Yoon YB, Lee KH, Park YS, Kim JW, Kim N, Lee DH, Jeong JB, Seo JS, Kim YT.
Spontaneous activation of pancreas trypsinogen in heat shock protein 70.1 knock-out mice. Pancreas. 2005 Nov;31(4):332-6.
Choi S, Park KA, Lee HJ, Park MS, Lee JH, Park KC, Kim M, Lee SH, Seo JS, Yoon BW.
Expression of Cu/Zn SOD protein is suppressed in hsp 70.1 knockout mice. J Biochem Mol Biol. 2005 Jan 31;38(1):111-4.
Lee BM, Park YJ, Park DS, Kang HW, Kim JG, Song ES, Park IC, Yoon UH, Hahn JH, Koo BS, Lee GB, Kim H, Park HS, Yoon KO, Kim JH, Jung CH, Koh NH, Seo JS, Go SJ.
The genome sequence of Xanthomonas oryzae pathovar oryzae KACC10331, the bacterial blight pathogen of rice. Nucleic Acids Res. 2005 Jan 26;33(2):577-86
Seo JS, Chong H, Park HS, Yoon KO, Jung C, Kim JJ, Hong JH, Kim H, Kim JH, Kil JI, Park CJ, Oh HM, Lee JS, Jin SJ, Um HW, Lee HJ, Oh SJ, Kim JY, Kang HL, Lee SY, Lee KJ, Kang HS.
The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4. Nat Biotechnol. 2005 Jan;23(1):63-8.

Publications - 2004

Yong Wook Kim, Su Mi Bae, Keun Ho Lee, Joon Mo Lee, Sung Eun Namkoong, Insu P. Lee, Chong Kook Kim, Jeong-Sun Seo, Jeong-Im Sin, Yong-Wan Kim, Woong Shick Ahn.
Comparison of As2O3 and As4O6 in the Detection of SiHa Cervical Cancer Cell Growth Inhibition Pathway. Cancer Research and Treatment. 2004;36(4):255-62.
Jin Hyeong Jhoo, Woong Yang Park, Ki Woong Kim, Kwang Hyuk Lee, Dong Young Lee, Jong Chul Youn, Young Ju Suh, Jeong-Sun Seo and Jong Inn Woo.
No Evidence of Association of Interleukin 1A(-889) Genetic Polymorphism with Alzheimer's Disease in Koreans. Genomics & Informatics. 2004 Jun;2(2):81-85.
Tomohiro Kono, Yayoi Obata, Quiong Wu, Katsutoshi Niwa, Yukiko Ono, Yuji Yamamoto, Eun Sung Park, Jeong-Sun Seo & Hidehiko Ogawa.
Birth of parthenogenetic mice that can develop to adulthood. Nature. 2004 Apr 22; 428(6985): 860-4.
Ahn WS, Bae SM, Lee JM, Namkoong SE, Han SJ, Cho YL, Nam GH, Seo JS, Kim CK, Kim YW.
Searching for pathogenic gene functions to cervical cancer. Gynecol Oncol. 2004 Apr; 93(1): 41-8.

Publications - 2002

Park WY, Hwang CI, Im CN, Kang MJ, Woo JH, Kim JH, Kim YS, Kim JH, Kim H, Kim KA, Yu HJ, Lee SJ, Lee YS, Seo JS.
Identification of radiation-specific responses from gene expression profile. Oncogene. 2002 Dec 5;21(55):8521-8.
Park HS, Cho SG, Kim CK, Hwang HS, Noh KT, Kim MS, Huh SH, Kim MJ, Ryoo K, Kim EK, Kang WJ, Lee JS, Seo JS, Ko YG, Kim S, Choi EJ.
Heat shock protein hsp72 is a negative regulator of apoptosis signal-regulating kinase 1. Mol Cell Biol. 2002 Nov;22(22):7721-30.
Shim EH, Kim JI, Bang ES, Heo JS, Lee JS, Kim EY, Lee JE, Park WY, Kim SH, Kim HS, Smithies O, Jang JJ, Jin DI, Seo JS.
Targeted disruption of hsp70.1 sensitizes to osmotic stress. EMBO Rep. 2002 Sep;3(9):857-61.
Kim SU, Park SK, Yoo KY, Yoon KS, Choi JY, Seo JS, Park WY, Kim JH, Noh DY, Ahn SH, Choe KJ, Strickland PT, Hirvonen A, Kang D.
XRCC1 genetic polymorphism and breast cancer risk. Pharmacogenetics. 2002 Jun;12(4):335-8.
Kwon SB, Young C, Kim DS, Choi HO, Kim KH, Chung JH, Eun HC, Park KC, Oh CK, Seo JS.
Impaired repair ability of hsp70.1 KO mouse after UVB irradiation. J Dermatol Sci. 2002 Feb:28(2):144-51.

Publications - ~1999

Young-Gyu Ko, Jae-Seon Lee, Young-Sun Kang, Jung-Hyuck Ahn and Jeong-Sun Seo,
TNF-a-Mediated Apoptosis Is Initiated in Caveolae-like Domains, J. Immunology, 162:7217-7223, 1999
Jung-Hyuck Ahn, Young-Gyu Ko, Woong-Yang Park, Young-Sun Kang, Hee Yong Chung and Jeong-Sun Seo,
Suppression of Ceramide-mediated Apoptosis by HSP70, Mol. Cells, 9(2):200-6, 1999
Byung Chul Yoo, Dong Ho Lee, Sill Moo Park, Joong Won Park, Chung Yong Kim, Hyo-Suk Lee, Jeong Sun Seo, Kie Jung Park, and Wang-Shick Ryu,
A Novel Parvovirus Isolated from Manchurian Chipmunks, Virology 253, 250-258 (1999)
Hyun-Jeong Kwak, Chang-Duk Jun, Hyun-Ock Pae, Ji-Chang Yoo, Young-Chul Park, Byung-Min Choi, Yong-Gil Na, Rae-Kil Park, Hun-Taeg Chung, Hee-Yong Chung, Woong-Yang Park, and Jeong-Sun Seo,
The role inducible 70-kDa heat shock protein in cell cycle control, differentiation, and apoptotic cell death of the human myeloid leukemic HL-60 cells, Cellular Immunology, Volume 187, NO. 1, July 10, 1998
Won-Ha Lee, Young-Mee Park, Jong-Il Kim, Woong-Yang Park, Soon-Hee Kim, Ja-June Jang, and Jeong-Sun Seo,
Expression of heat shock protein 70 blocks thymic differentiation of T cells in transgenic mice. Immunology 95(4):559-565, December, 1998
Seung-Sook Lee, Woong-Yang Park, Je Geun Chi, Jeong Wook Seo, Jong-Il Kim, Chul Woo KIm, Sung Hoe Park, Shin-Kwang Khang, Kyung-Ja Cho, Jeong-Sun Seo, Ja-June Jang,
Thymic epithelial tumour progression in an SV40T transgenic mouse model, Virchows Arch, 432: 33-42, 1998
Woong-Yang Park, Jong-Il Kim, Eun-Hee Shim, Won-Ha Lee, Soon-Hee Kim, Jung-Wook Seo, Ja-June Jang and Jeong-Sun Seo
Development of thymic carcinoma in transgenic mice expressing SV40 T antigen. Cancer Letters, 107(2) : 293-300, 1996
Jeong-Sun Seo, Young-Mee Park, Jong-Il Kim, Eun-Hee Shim, Chul-Woo Kim, Ja-June Jang, and Soon-Hee Kim and Won-Ha Lee,
T Cell Lymphoma in Transgenic Mice Expressing the Human HSP 70 Gene, Biochem Biophys Res Commun 218(2) : 582-587, 1996
Jong-Il Kim, Kyoungho Suk, Eun-Hee Shim, Soon-Hee Kim, Ja-June Jang, Kirsten Price, Marius Sudol and Jeong-Sun Seo,
Tumors Induced by Deregulated Expression of SH2 and SH3 Domains of Chicken c-Yes in Transgenic Mice, Mol. Cells, 5(6) : 641-644, 1995
Kyoungho Suk, Dae-Young Jung, Sung-Keun Kang, Sang-Won Kang, Eun Joo Seo, Hyun Ah Kang, Myeong-Hee Yu and Jeong-Sun Seo,
Human Erythropoietin-induced Polycythemia in Transgenic Mice, Mol. Cells, 5(6) : 634-640, 1995
Jeong-Sun Seo, So-Hee Hong, Woong-Yang Park, Sang-Eun Lee and Young-Kyoon Kim,
Expression of cellular oncogenes in transitional cell carcinomas of human bladder. Kor. J. Biochem., 21: 41, 1989
Byung Chul Yoo, Sil Moo Park, Chung Yong Kim, Hyo Sook Park and Jeong-Sun Seo,
A virus similar to human hepatitis B virus in manchurian chipmunks. Kor. J. Int. Med., 3: 102, 1988
Hong-Keun Chung, Joo-Bae Park, Jeong-Sun Seo, Pann-Ghill Suh, Heui-Jung Pyo, Bong-Hwa Lee and Nam-Mo Moon,
Purifications of Carcinoembryonic antigen from human colorectal cancer tissues. The Korean Journal of Biochemistry, 17(1): 67-72, 1985

Professor

JEONG-SUN SEO M.D., Ph.D.
JONG-IL KIM M.D., Ph.D.

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